Malaria‐Filaria Coinfection in Mice Makes Malarial Disease More Severe unless Filarial Infection Achieves Patency

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Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency.

Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria. For example, type 1-dependent control of malaria parasitemia might be impaired by the type 2 milieu of preexisting helminth infection. Alternatively, immunomodulatory effects of helminths might affect the likelihood of malarial immunopathol...

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 2005

ISSN: 0022-1899,1537-6613

DOI: 10.1086/426871